Caloric Restriction vs. Plant-Based Diets

Comments 84

  • Is it possible to lift weights, make gains, and not destroy your health?

  • Seems I can keep eating my 30 bananas a day ! 😀

  • Great video!!!

  • I love the fact that I can eat in abundance with the vegan lifestyle!

  • Fascinating! Great use of supporting research.

    3:45 Is it reduced animal protein intake or any-kind of protein intake?

  • Reduced IGF-1 also means far less muscle gains and far more muscle loss, which is dangerous in and by itself.

  • Hi, what about protein plant base as (Garden of Life )
    Thank you so much.

  • I liked this video,   my only criticism is that exercises raise IGF1  So of course ultra marathoners are going to have a higher IGF 1

  • very interesting

  • what's your opinion on high calorie, high protein vegan diet?
    what effects would it have on the body long term, compared to a non vegan one?
    thx 🙂

  • Very interesting indeed! 

  • Great video. Thank you.

  • Can someone answer this please anyone ? 

    Why are there people who eat animal products (i'm talking a couple times a day) who are very slim ??? I thought it was because they were young but now that I think about it I know adults who have passed 60 years old who are slimmer than I am (and I'm 18), is it because they don't eat enough calories to gain fat ?

    For instance my dad has been omnivorous all his life and never cut calories and yet he has a slim figure – with a 'lil belly – but like he's not overweight or obese…

    Also, I know a ton of people (this time young, teenagers) who can eat all the fatty foods in the world but not gain one ounce, is there some kind of scientific explanation to this ???

  • One of my favorite videos you've made. Your the best Dr. Gregor.

  •  Dr. Greger is the man.

  • I love eating all I care for on my vegan diet!

  • It would be nice to see the last study done again with more people. One study alone should be taken cautiously until it has been replicated.

  • Now we need a study that compares low intake of animal protein vs low intake of plant protein to see if it's just the micronutrient ratios/amounts or the source of the micronutrients that lowers Igf1…

  • The next study they should do should compare the overall health of those who watch and those who do not watch Dr. Greger's videos. One guess as to who would win 😀

  • Back to veganism for me. Thank you, Dr. Gregor.

  • Does plant-based protein have the same kind of effect on the IGF levels as animal based protein?

  • Damm…..this guy's voice is so smug.  It's dripping with arrogance and smug boredom common to people who wear white lab coats. Bleh..I wish his videos were captioned, so I could turn off his arrogant junior college professor voice….. yeech.

  • Great point makes sense !!!

  • @paintur68 No, you didn't ; You implied.

  • Caloric restriction vs. plant-based diets are put to the test to see which best lowers cancer promoter IGF-1.

    Watch below or click the link to watch on

  • Excellent, thank you!

  • A diet high in starch and sugar is a lot of it when it comes to overweight. The problem is starch is cheap fuel and people are hard wired to love sweets. Many people can't even begin to afford what you want them to eat. One 20 oz soft drink a day at 250 calories and in 7 days they drink 1750 calories with no other nutritional value. That soft drink alone means they eat enough calories for another entire extra day and in a form that almost dumps all the calories in the blood stream super fast as they drink it. 

  • Why did you show Nathan Pritikin when you said role in preventing cancer? He contracted leukemia after many years on plant based diet.  
    I am a big fan of Nathan but was wondering what happened. 

  • plant based diets suck …BV IS FAR GREATER IN WHEY …plant based diets suck …run from this doctor

  • everything on the human body is protein based…your skin, hair, muscles etc…this doctor is anti-muscle, anti-sex appeal …wish he would work out

  • protein intake, does this mean veg or animal , or does it matter

  • The last point would concur with Colin Campbell's finding in the China Study, that protein intake above 8% is linked to incidence of cancer. This percentage protein intake can be achieved on a plant based diet. Good vid., thanks

  • IGF-1 causes cancer? You need to do more research on that… maybe cancer increases igf-1?
    You went from cancer to IGF1 and forgot all about cancer… What about the comparisons of the runners, vegans etc on cancer?
    Who lives longer?
    No vegan has gone 100+ years

  • I'd rather die of cancer than become vegan. Serious.

  • Best health channel, thanks !

  • If I want to balance my diet on chronometer, which vitamins and minerals would not be necessary to get a 100% each day? I mean not because they are less important but because the body has at least a short term reserve of them?

  • I wonder if there is a difference between animal proteins and plant-based proteins in raising IDF-1.

  • Two years ago I started a to be vegan after 31 years of being a vegetarian.

    I can feel my body fat has reduced but not enough considering that 5 months ago I gave birth my second daughter, I tried the raw vegan lifestyle as well and It was a good experience but I like eating potatoes, rice, etc… 😉

    The Low fat vegan lifestyle is great!!!

  • This Dr. John McDougall pointed out very well, when he discussed the Rice-Diet he claims to be the best diet for severe illnesses. This diet will keep the protein-level and the fat-level very low this is why it even uses white rice because wholegrain rice has much more protein. I do not know yet, what my opinion is about that. I certainly like white rice very much, but my guts tell me, that wholegrain is far better! What do you think?

  • stupid Dr

  • Feels bad being someone who wants to gain some muscle now :S

  • "Cute names with not so cute side effects" hahahahhaa

  • If you want to lose weight, you should look up Fenoboci Diet Plan on the internet. They'll make it easier to get the shape you should have.

  • Hi there, have you thought about this kind of diet plan called the Fenoboci Diet Plan? My work buddy says it helps people lost a lot of weight. Is that possible? I also read a lot of good review relating to this diet plan. Thoughts?

  • You are a good scientist😇😇😇😇😇😇

  • In the animal studies the animals were given stellar nutrition, while being given just less calories. But in real life outside of the labs, are people able to get perfect nutrition, as did the lab animals? Further is IGF 1 the sole determinate of longevity?

  • You really stress plant based diet.  However, I have a question:   What about meat flavorings?   I really like chicken broth, or use bouillon in my vegetable soup.   I could go without meat as a main item, but what about meat broth as flavoring or as base for veggie soups?

  • "One gram of fiber for every one hundred calories." If you only eat food that meets this requirement and only drink water then you will maintain the appropriate weight. All plant based foods have fiber.

  • The conclusion suggests that protein intake regardless of source is detrimental. Did I misunderstand?

  • Could it be that cancer cells cause an increase in IGF-1 and not the other way around? Also, the issue is so controversial and the findings between humans vs other species are different, that it is hard to make any decisions about manipulating IGF-1 for healthy individuals. Here is an excerpt from an interesting article: "A meta-analysis of studies examining the correlation between high IGF-1 levels and different cancers only found increased risk of prostate and pre-menopausal breast cancers, suggesting that perhaps it’s premature to say that high levels of IGF-1 would predispose someone to cancer. There are many more cancers, and many more deadly cancers, that did not appear to be highly correlated.

    A second meta-analysis observed that men with low IGF-1 levels actually had significantly higher risk of death due to cancer than men with normal (not high) levels. In this case, no studies involving cancer risk and IGF-1 in women were included, so we cannot assume the same will be true in women–though we might expect it to be similar given our knowledge of how IGF-1 affects the human body."

  • having a videos about high carb low fat vegans (who eat 3000/4500 calories a day) and the science behind it (would they have the same results as the lower calorie vegan group ? ) and also the ideal macro ratio for health (low fat ? moderate fat ? etc) would be awesome.

  • Just combine both. A plant-based diet with caloric restriction. Benefits from both paradigms? 🙂

  • "You can be healthy at any size!!!!!!!!!!!!!!!11!1!!!!!!!!!!!!!!!!" – Delusional people

  • True a low protein diet lowers ur growth hormone levels but if u want to repair damaged cells and neuropathways u need IGF-1 for this function.

  • A really good resource to look into is a book called The China Study by Dr. Campbell. There are some great videos on youtube of his lectures. It would help shed light on some questions that this video may have raised. Similar findings but Dr. Colin T. Campbell really goes in depth about the roles of plant protein vs. animal protein and its effect on cancer, tumours, and other diseases. Then, to find out where he came from and his motives for conducting this huge scientific study is mind blowing. Don't try to guess…because you won't guess it.

  • Great video. There is however one correlation that I wish you would have put in with your findings. You said it may just be the lower protein consumption overall by the vegans. But, the thing you didn't 'put to the test' was whether it was not just lower protein, but whether it was plant protein VS the animal protein?
    Being a 5 foot 7 200lb vegan myself I consume 130 plus grams of protein per day. So, this would be of particular interest to me.
    Thank you very much for all that you do.

  • Maybe the best strategy is to eat all the meat and eggs and dairy products you want during childhood (including late childhood/adolescence), but once you hit 18, you should go plant-based! 😀

  • hello i AM from Argentina. i like if every videos have subtitle

  • Is it possible sugar is and refined card are the primary reason the IG1 is lower in a vegan diet?

  • What about fasting?

  • it's amazing how hard the vegan diets hits it out of the ballpark here. even if caloric intake were held constant, veganism would win, but it's not, so veganism wins by twice the margin!

  • I feel like we need an update on this. What new research has come out to compare CR vs low protein?

  • Everything is fine and dandy, but when i starting eating nuts, seeds and avocados, i start to get jiggly "downstairs". So…should i limit them? like 1 tbsp on flax or? what do i do? (i'm a really big volume eater, and do great on starches, vegetables and fruits)

  • Vegans have the lowest levels of IGF 1. Let's start with the fact (or assumption) that a man is a vegan, and in that context, let's look at an experiment with caloric restriction on rodents. Do vegans, who are exposed to calorie restriction, have even lower levels of IGF 1 than vegans that eat normal amounts of food?
    And, what about the vegans who apply a water fasting, say 7-15 related days for every 3 months, or 4-5 related days each month, or 36h once a week? Does the water post make sense and benefit from the vegan?

  • I'm learning so much, thank you

  • Low protein intake is protective? But what if I wanna build muscle AND live a long life? Is eating alot of protein from plants risky too?

  • My cousin was skinny like a toothpick. He was having a barbecue every end of the week and heavy meat and olive oil eater being italian. He died on his sleep at just 50 years of age leaving 2 very young daughters and a shocked, devastated wife. He died of a coronary arterial blockage. Skinny people are not immune from heart and arterial disease.

  • Should one be concerned about eating too much plant based protein?

  • Do you me meat protien or protien altogether?

  • Plant based diets CAN be compatible with diet restrictions, but not if you pack your self full of starch plant foods

  • Caloric restriction can just mean don't eat the average excessive intake.

  • Whole Foods, low fat, plant-based is the way to go.

  • The world is waking up! Raw Vegan/Fruitarianism brings us back to our natural, species specific, diet. It’s no wonder all of our modern, man made, ‘dis-eases’ fade so quickly when we adhere to the natural laws of this bountiful planet. Live in abundance my friends, and say goodbye to the ails of this age.

  • Biased. Long distance runners have been shown to produce high levels of inflammatory cytokines as well as atrial fibrosis on account of extreme physical exertion.

  • Great video, very well put together. However, I was left a little confused at the end of the video. Does the conclusion mean that less protein consumption (from any food source) could lower the risk of potential cancer disease or lowering the consumption of animal protein alone can potentially lower the risk of cancer disease?
    I don't know if it's just me, but I would love if someone clarifies that for me!
    Nonetheless, an amazing video. I love ya'll stuff!

  • Wow! That was summarized quickly. Thanks

  • Calorie restriction vs intermittent fasting vs vegan diet for longevity and health?

  • If you read the book of Genesis, mankind was ordered by God to be vegan, up until the Great Flood. And while mankind was vegan people lived extremely long lives, up to 900 years of age,

  • I´ve been watching some of the My 600lb life show, and I know that doctor is trying to help, but… He´s putting these obese people who suffer from eating disorders on a 1200 cal no carb diet :(… And then wonders why they fail. I´m really shocked he doesn´t know any better.

  • well so is it the plant based diet that reduces cancer risk, or reduced protein intake? because one can eat mostly animal foods, and not eat too much protein

  • Less fat, less cancer.  So what's the argument.

  • Same study shows, when they took some of the CR individuals and reduced their protein intake by 56%, they get to 152ng/ml of IGF1 just after a few weeks. That’s almost vegan levels. Cherry picking data 👎

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